Description
SP6 Antibody (PACO12407)
The SP6 Monoclonal Antibody (PACO12407) is a valuable tool for researchers studying SP6, a transcription factor known for its role in gene regulation and cell differentiation. This antibody, produced through hybridoma technology, has been shown to have high specificity and sensitivity in detecting SP6 in a variety of cell types.SP6 is a transcription factor that plays a crucial role in the regulation of gene expression, particularly in embryonic development and tissue differentiation. Dysregulation of SP6 has been implicated in various diseases, making it a promising target for therapeutic interventions.
The SP6 Monoclonal Antibody enables researchers to study the expression and activity of SP6 in both normal and pathological conditions, providing valuable insights into its function and potential clinical applications. Whether investigating stem cell differentiation, developmental biology, or disease mechanisms, the SP6 Monoclonal Antibody offers a reliable tool for detecting and analyzing SP6 expression, contributing to advancements in basic science and translational research.
Antibody Name: | SP6 Antibody (PACO12407) |
Antibody SKU: | PACO12407 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human SP6 |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | Sp6 transcription factor;SP6;EPFN;EPIPROFIN;KLF14;MGC119662;MGC119663;MGC119664;MGC119665 ; |
UniProt Protein Function: | SP6: Promotes cell proliferation. Belongs to the Sp1 C2H2-type zinc-finger protein family. |
UniProt Protein Details: | Protein type:DNA-binding; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 17q21.32 |
NCBI Summary: | SP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q3SY56 |
NCBI GenInfo Identifier: | 82582258 |
NCBI Gene ID: | 80320 |
NCBI Accession: | Q3SY56.1 |
UniProt Secondary Accession: | Q3SY56,B3KXS4, |
UniProt Related Accession: | Q3SY56 |
Molecular Weight: | 39,840 Da |
NCBI Full Name: | Transcription factor Sp6 |
NCBI Synonym Full Names: | Sp6 transcription factor |
NCBI Official Symbol: | SP6 |
NCBI Official Synonym Symbols: | EPFN; KLF14; EPIPROFIN |
NCBI Protein Information: | transcription factor Sp6 |
UniProt Protein Name: | Transcription factor Sp6 |
UniProt Synonym Protein Names: | Krueppel-like factor 14 |
Protein Family: | Transcription factor |
UniProt Gene Name: | SP6 |
UniProt Entry Name: | SP6_HUMAN |