SP3 Rabbit Polyclonal Antibody (CAB12790)
- SKU:
- CAB12790
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | SP3 Rabbit Polyclonal Antibody |
SKU: | CAB12790 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 705-781 of human SP3 (NP_003102.1). |
Sequence: | NKKG IHSS STVL ASVE AARD DTLI TAGG TTLI LANI QQGS VSGI GTVN TSAT SNQD ILTN TEIP LQLV TVSG NETM E |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | SPR2; SP3 |
Positive Sample: | A-549,PC-3,Mouse liver,Mouse brain,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, PML body. |
Calculated MW: | 82kDa |
Observed MW: | 70kDa |
This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
Purification Method: | Affinity purification |
Gene ID: | 6670 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |