The SP3 Polyclonal Antibody (CAB12790) is a powerful tool for researchers studying SP3, a transcription factor involved in gene regulation and cell differentiation. This antibody, developed using rabbit immunization, has high specificity and sensitivity for detecting SP3 in human samples, making it an ideal choice for Western blot and immunohistochemistry applications.SP3 is a key player in cell growth, development, and differentiation, making it a crucial target for studies in cancer research and stem cell biology.
By enabling precise detection and analysis of SP3 protein levels in various cell types, this antibody provides valuable insights into the mechanisms underlying these biological processes.The versatile nature of the SP3 Polyclonal Antibody makes it a valuable asset for researchers exploring the role of SP3 in various cellular pathways and disease states. Its reliability and quality make it a trusted tool for advancing scientific knowledge and uncovering new therapeutic targets related to SP3 function.
Product Name:
SP3 Rabbit Polyclonal Antibody
SKU:
CAB12790
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 705-781 of human SP3 (NP_003102.1).
This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
Purification Method:
Affinity purification
Gene ID:
6670
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SP3 Rabbit pAb (CAB12790) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
