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SP2 Transcription Factor Activity Assay

SKU:
TFAB00161
Product Type:
ELISA Kit
ELISA Type:
Transcription Factor Assay
Analytes:
SP2
Reactivity:
Human
Mouse
$719
Frequently bought together:

Description

system_update_altDatasheet

SP2 Transcription Factor Activity Assay

The SP2 Transcription Factor Activity Assay Kit is specifically designed for the detection and quantification of SP2 transcription factor activity in various biological samples. This kit offers high sensitivity and accuracy, allowing researchers to obtain reliable and reproducible results for their studies.SP2 is a transcription factor that plays a key role in regulating gene expression and cell growth. It is involved in various cellular processes, including cell differentiation, proliferation, and apoptosis. Dysregulation of SP2 activity has been associated with a variety of diseases, such as cancer, diabetes, and neurodegenerative disorders.

By utilizing the SP2 Transcription Factor Activity Assay Kit, researchers can gain valuable insights into the role of SP2 in disease development and progression. This kit is suitable for a wide range of research applications and provides a convenient and efficient method for studying SP2 transcription factor activity. Trust in the accuracy and reliability of this assay kit to advance your research efforts in the field of transcription factor biology.

Product Name:SP2 Transcription Factor Activity Assay
Product Code:TFAB00161
Target:SP2
Reactivity:Human, Mouse
Sample Types:Nuclear or cell lysates

The Assay Genie SP2 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates

Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.

Assay Time:4.5 hours
Detection Method:Colorimetric 450 nm
Size:12 x 8-Well Microstrips
Storage:4°C for 6 months
UniProt Protein Function:SP2: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Belongs to the Sp1 C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:DNA-binding; Transcription factor; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 17q21.32

Cellular Component: nucleus

Molecular Function:histone deacetylase binding; protein binding

Biological Process: immune response; regulation of transcription from RNA polymerase II promoter

NCBI Summary:This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008]
UniProt Code:Q02086
NCBI GenInfo Identifier:119370531
NCBI Gene ID:6668
NCBI Accession:Q02086.3
UniProt Secondary Accession:Q02086,A6NK74,
UniProt Related Accession:Q02086
Molecular Weight:64,153 Da
NCBI Full Name:Transcription factor Sp2
NCBI Synonym Full Names:Sp2 transcription factor
NCBI Official Symbol:SP2  
NCBI Protein Information:transcription factor Sp2
UniProt Protein Name:Transcription factor Sp2
Protein Family:Sex-specific storage-protein
UniProt Gene Name:SP2  
UniProt Entry Name:SP2_HUMAN
Antibodies
SP2 Antibody (PACO05109)

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