The SP2 Polyclonal Antibody (CAB20711) is a vital tool for researchers studying the SP2 protein, which plays a key role in transcriptional regulation and cell differentiation. This antibody is produced in rabbits and is highly specific for human samples, making it ideal for use in Western blot applications. By binding to the SP2 protein, this antibody enables the detection and analysis of SP2 expression in various cell types, offering valuable insights into developmental biology and cancer research.
SP2 is a transcription factor that is involved in the regulation of gene expression, particularly during development and differentiation processes. Its function in controlling cell fate and identity makes it a crucial target for investigation in areas such as stem cell research and oncology. By understanding the role of SP2 in these contexts, researchers can potentially uncover new therapeutic targets for treating various diseases and disorders.
Product Name:
SP2 Polyclonal Antibody
SKU:
CAB20711
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-331 of human SP2 (NP_003101.3).
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.
Purification Method:
Affinity purification
Gene ID:
6668
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using (CAB20711) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
