SP140 Rabbit Polyclonal Antibody (CAB17634)
- SKU:
- CAB17634
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SP140 Rabbit Polyclonal Antibody |
SKU: | CAB17634 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SP140 (NP_001265380). |
Sequence: | MAQQ GQQG QMAS GDSN LNFR MVAE IQNV EGQN LQEQ VCPE PIFR FFRE NKVE IASA ITRP FPFL MGLR DRSF ISEQ MYEH FQEA FRNL VPVT RVMY CVLS ELEK TFGW SHLE ALFS RINL MAYP DLNE IYRS FQNV CYEH SPLQ MNNV NDLE DRPR LLPY GKQE NSNA CHEM DDIA VPQE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LYSP100; LYSP100-A; LYSP100-B; SP140 |
Positive Sample: | Mouse spleen,Mouse thymus,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | fibrillar center, mitochondrion, nucleus, PML body |
Calculated MW: | 98kDa |
Observed MW: | 98kDa |
This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants.
Purification Method: | Affinity purification |
Gene ID: | 11262 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |