The SP110 Polyclonal Antibody (CAB7492) is a valuable tool for researchers studying the SP110 protein, which plays a key role in regulating immune responses and inflammation. This antibody is produced in rabbits and has been validated for use in Western blot applications, ensuring reliable and accurate results.SP110 is a nuclear protein that is involved in the regulation of immune gene expression, making it a crucial player in the immune system. By targeting the SP110 protein, researchers can gain insights into its function and potentially develop new treatments for conditions related to immune dysfunction.
This antibody is highly specific to human samples, providing researchers with a powerful tool for studying the role of SP110 in various diseases, including cancer, autoimmune disorders, and inflammatory conditions. With its high reactivity and specificity, the SP110 Polyclonal Antibody is an essential addition to any research lab studying immune regulation and inflammation.
Product Name:
SP110 Rabbit Polyclonal Antibody
SKU:
CAB7492
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human SP110 (NP_004501.3).
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.
Purification Method:
Affinity purification
Gene ID:
3431
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SP110 antibody (CAB7492) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 30s.
