SP100 Rabbit Polyclonal Antibody (CAB5851)
- SKU:
- CAB5851
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | SP100 Rabbit Polyclonal Antibody |
SKU: | CAB5851 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 181-480 of human SP100 (NP_001193631.1). |
Sequence: | FRSL TWPP SGSP SHAG TTPP ENGL SEHP CETE QINA KRKD TTSD KDDS LGSQ QTNE QCAQ KAEP TESC EQIA VQVN NGDA GREM PCPL PCDE ESPE AELH NHGI QINS CSVR LVDI KKEK PFSN SKVE CQAQ ARTH HNQA SDII VISS EDSE GSTD VDEP LEVF ISAP RSEP VINN DNPL ESND EKEG QEAT CSRP QIVP EPMD FRKL STFR ESFK KRVI GQDH DFSE SSEE EAPA EASS GALR SKHG EKAP MTSR STST WRIP SRKR RFSS SDFS DLSN GEEL QETC SSSL RRGS GKED |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | lysp100b; SP100 |
Positive Sample: | MCF7,HeLa,293T,HepG2,Mouse spleen,Mouse thymus,Mouse lung,Mouse heart,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, PML body. |
Calculated MW: | 100kDa |
Observed MW: | 66-100kDa |
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
Purification Method: | Affinity purification |
Gene ID: | 6672 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |