SP1 Rabbit Monoclonal Antibody (CAB19649)
- SKU:
- CAB19649
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SP1 Rabbit Monoclonal Antibody |
SKU: | CAB19649 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human SP1 (P08047). |
Sequence: | TTLT PIAS AASI PAGT VTVN AAQL SSMP GLQT INLS ALGT SGIQ VHPI QGLP LAIA NAPG DHGA QLGL HGAG GDGI HDDT AGGE EGEN SPDA QPQA GRRT R |
Tested Applications: | WB IHC-P IF/ICC ChIP ChIP-seq ELISA CUT&Tag |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 ChIP,5μg antibody for 10μg-15μg of ChromatinCUT&Tag, 10⁵ cells /1 μgChIP-seq,1:50 - 1:100 |
Synonyms: | SP1 |
Positive Sample: | HeLa, U-87MG, Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 81kDa |
Observed MW: | 90kDa |
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6667 |
Clone Number: | ARC0128 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |