The SOX9 Polyclonal Antibody (CAB2479) is a valuable tool for researchers studying SOX9, a transcription factor that plays a critical role in development and disease. This antibody, generated in rabbits, is highly specific to human SOX9 and has been validated for use in Western blot and immunohistochemistry applications.SOX9 is essential for the regulation of embryonic development, particularly in the formation of cartilage, bone, and other tissues. Dysregulation of SOX9 has been implicated in a variety of diseases, including skeletal disorders and cancer.
The SOX9 Polyclonal Antibody enables accurate detection and visualization of SOX9 in various cell types, making it an indispensable tool for studies in developmental biology, regenerative medicine, and oncology.By investigating the expression and function of SOX9, researchers can gain valuable insights into the molecular mechanisms underlying disease pathogenesis and potential therapeutic strategies. The SOX9 Polyclonal Antibody is a reliable resource for advancing our understanding of SOX9 biology and its impact on health and disease.
Product Name:
SOX9 Rabbit Polyclonal Antibody
SKU:
CAB2479
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-339 of human SOX9 (NP_000337.1).
The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Purification Method:
Affinity purification
Gene ID:
6662
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using SOX9 Rabbit pAb (CAB2479) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
