The SOX4 Polyclonal Antibody (CAB10717) is a valuable tool for researchers studying the SOX4 gene, a transcription factor involved in various biological processes, including cell differentiation and embryonic development. This antibody, raised in rabbits, shows high reactivity with human samples and is validated for use in Western blot and immunohistochemistry applications.SOX4 is known to play a key role in regulating gene expression and cellular processes, making it a significant target for studies in developmental biology, cancer research, and stem cell research. By binding specifically to the SOX4 protein, this antibody enables precise detection and analysis in a variety of cell types, allowing for detailed investigation into the functions and mechanisms of SOX4 in different contexts.
Researchers exploring the role of SOX4 in cancer progression or investigating its potential as a therapeutic target will find this antibody to be a valuable asset in their experiments. With its high specificity and reliability, the SOX4 Polyclonal Antibody (CAB10717) provides researchers with a powerful tool to advance their understanding of SOX4 biology and its implications in various diseases.
Product Name:
SOX4 Rabbit Polyclonal Antibody
SKU:
CAB10717
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SOX4 (NP_003098.1).
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
Purification Method:
Affinity purification
Gene ID:
6659
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Mouse brain, using SOX4 antibody (CAB10717) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
