The SOX30 Polyclonal Antibody (CAB11715) is a valuable tool for researchers studying SOX30, a transcription factor that plays a crucial role in developmental processes and cell differentiation. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications.SOX30 is known to be involved in regulating gene expression and is essential for proper development of various tissues, including the nervous system, heart, and skeletal muscles. Its dysregulation has been associated with developmental disorders and diseases such as cancer.
By targeting the SOX30 protein, this antibody allows for the detection and analysis of SOX30 expression in different cell types, making it ideal for studies in development biology, stem cell research, and cancer biology. Understanding the function of SOX30 and its role in various biological processes is crucial for advancing our knowledge in these fields and potentially identifying new therapeutic targets.
Product Name:
SOX30 Rabbit Polyclonal Antibody
SKU:
CAB11715
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 604-753 of human SOX30 (NP_848511.1).
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein acts as a transcriptional regulator when present in a complex with other proteins. It can activate p53 transcription to promote tumor cell apoptosis in lung cancer. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 5.
Purification Method:
Affinity purification
Gene ID:
11063
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SOX30 Rabbit pAb (CAB11715) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
