[KO Validated] SOX2 Rabbit Polyclonal Antibody (CAB0561)
- SKU:
- CAB0561
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | [KO Validated] SOX2 Rabbit Polyclonal Antibody |
SKU: | CAB0561 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SOX2 (NP_003097.1). |
Sequence: | MYNM METE LKPP GPQQ TSGG GGGN STAA AAGG NQKN SPDR VKRP MNAF MVWS RGQR RKMA QENP KMHN SEIS KRLG AEWK LLSE TEKR PFID EAKR LRAL HMKE HPDY KYRP RRKT KTLM KKDK YTLP GGLL APGG NSMA |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | ANOP3; MCOPS3; SOX2 |
Positive Sample: | 293T,MCF7,Mouse lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 34kDa |
Observed MW: | 35kDa |
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Purification Method: | Affinity purification |
Gene ID: | 6657 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |