The SOX18 Polyclonal Antibody (CAB16536) is a valuable tool for researchers studying the SOX18 protein, which plays a crucial role in various cellular processes such as embryonic development, vascular remodeling, and lymphatic vessel development. This antibody, produced in rabbits, has high specificity for SOX18 and is suitable for Western blot applications in human samples.SOX18 is a transcription factor that regulates gene expression, contributing to the formation of blood and lymphatic vessels during development. Dysregulation of SOX18 has been linked to various diseases, including cardiovascular disorders and certain types of cancer.
By targeting SOX18 with this antibody, researchers can investigate its role in these diseases and potentially identify new therapeutic targets.With its ability to detect and quantify SOX18 protein levels in different cell types, the SOX18 Polyclonal Antibody is a valuable tool for studies in developmental biology, angiogenesis, and cancer research. By understanding the mechanisms by which SOX18 functions, researchers can pave the way for the development of novel treatments for a range of medical conditions.
Product Name:
SOX18 Rabbit Polyclonal Antibody
SKU:
CAB16536
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SOX18 (NP_060889.1).
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
Purification Method:
Affinity purification
Gene ID:
54345
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SOX18 Rabbit pAb (CAB16536) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
