The SOX14 Polyclonal Antibody (CAB13674) is a valuable tool for researchers studying SOX14, a transcription factor involved in the development of the nervous system and other tissues. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the SOX14 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in developmental biology and neurology.SOX14 plays a critical role in regulating gene expression during development, impacting processes such as cell differentiation and tissue formation.
Dysregulation of SOX14 has been linked to neurological disorders and developmental abnormalities, making it an important target for research in these areas. Understanding the functions of SOX14 is essential for gaining insights into disease mechanisms and potentially developing therapeutic strategies for related conditions.Overall, the SOX14 Polyclonal Antibody is a valuable tool for researchers investigating the roles of SOX14 in development and disease, providing accurate and reliable detection of this important transcription factor in various experimental settings.
Product Name:
SOX14 Rabbit Polyclonal Antibody
SKU:
CAB13674
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 91-240 of human SOX14 (NP_004180.1).
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus syndrome (BPES) and Mobius syndrome.
Purification Method:
Affinity purification
Gene ID:
8403
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using SOX14 Rabbit pAb (CAB13674) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
