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SOX12 Transcription Factor Activity Assay

SKU:
TFAB00199
Product Type:
ELISA Kit
ELISA Type:
Transcription Factor Assay
Analytes:
SOX12
Reactivity:
Human
Mouse
$719
Frequently bought together:

Description

system_update_altDatasheet

SOX12 Transcription Factor Activity Assay

The SOX12 Transcription Factor Activity Assay offered by Assay Genie is a cutting-edge tool for the precise measurement of SOX12 transcription factor activity in a variety of experimental samples. This assay boasts exceptional sensitivity and specificity, guaranteeing accurate and consistent results for a diverse array of research endeavors.SOX12 is a key transcription factor responsible for regulating gene expression and influencing cellular processes such as differentiation, development, and proliferation. Its role in various biological pathways makes it a valuable target for studying conditions such as cancer, developmental disorders, and neurological diseases.

By utilizing the SOX12 Transcription Factor Activity Assay, researchers can gain valuable insights into the intricate mechanisms underlying these conditions, paving the way for the development of innovative therapeutic strategies. Trust Assay Genie to provide you with a reliable and efficient solution for exploring the fascinating world of SOX12 transcription factor activity.

Product Name:SOX12 Transcription Factor Activity Assay
Product Code:TFAB00199
Target:SOX12
Reactivity:Human, Mouse
Sample Types:Nuclear or cell lysates

The Assay Genie SOX12 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates

Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.

Assay Time:4.5 hours
Detection Method:Colorimetric 450 nm
Size:12 x 8-Well Microstrips
Storage:4°C for 6 months
UniProt Protein Function:Function: Binds to the sequence 5'-AACAAT-3'
UniProt Protein Details:

By similarity.

Subcellular location: Nucleus Ref.1.

Tissue specificity: Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive. Ref.1

Sequence similarities: Contains 1 HMG box DNA-binding domain.

Sequence caution: The sequence AAB69627.1 differs from that shown. Reason: Frameshift at positions 135 and 201.

NCBI Summary:Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013]
UniProt Code:O15370
NCBI GenInfo Identifier:21264339
NCBI Gene ID:6666
NCBI Accession:NP_008874
UniProt Related Accession:O15370
Molecular Weight:34kDa
NCBI Full Name:transcription factor SOX-12
NCBI Synonym Full Names:SRY-box 12
NCBI Official Symbol:SOX12  
NCBI Official Synonym Symbols:SOX22  
NCBI Protein Information:transcription factor SOX-12
UniProt Protein Name:Transcription factor SOX-12
UniProt Synonym Protein Names:Protein SOX-22
Protein Family:Transcription factor
UniProt Gene Name:SOX12  
UniProt Entry Name:SOX12_HUMAN
Antibodies
SOX12 Antibody (PACO05107)

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