SOX12 Antibody (PACO05107)
- SKU:
- PACO05107
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
SOX12 Antibody (PACO05107)
The SOX12 Polyclonal Antibody (PACO05107) is a valuable tool for researchers studying the SOX12 protein, which plays a critical role in development and cell differentiation. This antibody, generated in rabbits, displays high reactivity with human samples and has been extensively validated for use in Western blot applications. By targeting the SOX12 protein, this antibody enables detection and analysis in a variety of cell types, making it an essential resource for studies in developmental biology and cancer research.SOX12, a member of the SOX (SRY-related HMG-box) family of transcription factors, is known for its involvement in embryonic development and tissue-specific gene regulation.
Its function in these processes highlights its potential significance in diseases such as cancer and genetic disorders. Investigating the role of SOX12 can provide valuable insights into the mechanisms underlying these conditions and may lead to the development of novel therapeutic strategies targeting this protein.Overall, the SOX12 Polyclonal Antibody (PACO05107) offers researchers a reliable tool for investigating the function and expression of the SOX12 protein in various biological contexts. Its specificity and sensitivity make it a valuable asset for advancing our understanding of developmental processes and disease mechanisms.
| Antibody Name: | SOX12 Antibody (PACO05107) |
| Antibody SKU: | PACO05107 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:20000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from the Internal region of human Sox-12. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | SOX12; SOX22; Transcription factor SOX-12; Protein SOX-22 |
| UniProt Protein Function: | Function: Binds to the sequence 5'-AACAAT-3' |
| UniProt Protein Details: | By similarity. Subcellular location: Nucleus Ref.1. Tissue specificity: Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive. Ref.1 Sequence similarities: Contains 1 HMG box DNA-binding domain. Sequence caution: The sequence AAB69627.1 differs from that shown. Reason: Frameshift at positions 135 and 201. |
| NCBI Summary: | Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013] |
| UniProt Code: | O15370 |
| NCBI GenInfo Identifier: | 21264339 |
| NCBI Gene ID: | 6666 |
| NCBI Accession: | NP_008874 |
| UniProt Related Accession: | O15370 |
| Molecular Weight: | 34kDa |
| NCBI Full Name: | transcription factor SOX-12 |
| NCBI Synonym Full Names: | SRY-box 12 |
| NCBI Official Symbol: | SOX12Â Â |
| NCBI Official Synonym Symbols: | SOX22Â Â |
| NCBI Protein Information: | transcription factor SOX-12 |
| UniProt Protein Name: | Transcription factor SOX-12 |
| UniProt Synonym Protein Names: | Protein SOX-22 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | SOX12Â Â |
| UniProt Entry Name: | SOX12_HUMAN |
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