The SOX10 Polyclonal Antibody (CAB15100) is a crucial tool for researchers studying SOX10, a transcription factor involved in the development and function of neural crest-derived cell types. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for Western blot applications.SOX10 is known for its role in the regulation of genes essential for the differentiation of melanocytes, Schwann cells, and oligodendrocytes. Dysregulation of SOX10 has been implicated in various diseases, including neurocristopathies and certain types of cancer.
Therefore, studying the expression and activity of SOX10 using this antibody can provide valuable insights into developmental processes and disease mechanisms.With its ability to detect and quantify SOX10 protein levels in a wide range of cell types, the SOX10 Polyclonal Antibody is a valuable tool for researchers in the fields of developmental biology, neurobiology, and oncology. Gain a deeper understanding of SOX10 function and its implications in health and disease with this reliable antibody.
Product Name:
SOX10 Rabbit Polyclonal Antibody
SKU:
CAB15100
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 270-360 of human SOX10 (NP_008872.1).
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
Purification Method:
Affinity purification
Gene ID:
6663
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SOX10 Rabbit pAb (CAB15100) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
