The Sorting Nexin 9 Polyclonal Antibody (CAB0977) is a crucial tool for researchers studying the role of Sorting Nexin 9, a protein involved in intracellular trafficking and membrane dynamics. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards Sorting Nexin 9 in human samples, making it ideal for applications such as Western blot analysis.Sorting Nexin 9 is known to participate in various cellular processes, including endosomal sorting and recycling pathways, making it a key player in cell homeostasis and signaling. Dysregulation of Sorting Nexin 9 has been linked to various diseases, such as neurodegenerative disorders and cancer, highlighting its importance in physiological and pathological conditions.
By utilizing the Sorting Nexin 9 Polyclonal Antibody, researchers can effectively visualize and quantify Sorting Nexin 9 protein levels in different cell types and experimental models. This antibody's reliability and specificity make it a valuable tool for investigating the molecular mechanisms underlying cellular processes involving Sorting Nexin 9, ultimately advancing our understanding of its potential therapeutic implications in various diseases.
Product Name:
SNX9 Rabbit Polyclonal Antibody
SKU:
CAB0977
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SNX9 (NP_057308.1).
This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, but does contain a SRC homology domain near its N-terminus. The encoded protein is reported to have a variety of interaction partners, including of adaptor protein 2 , dynamin, tyrosine kinase non-receptor 2, Wiskott-Aldrich syndrome-like, and ARP3 actin-related protein 3. The encoded protein is implicated in several stages of intracellular trafficking, including endocytosis, macropinocytosis, and F-actin nucleation.
Purification Method:
Affinity purification
Gene ID:
51429
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SNX9 Rabbit pAb (CAB0977) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
