The Sorting Nexin 18 Polyclonal Antibody (CAB10337) is a valuable tool for research involving Sorting Nexin 18 (SNX18), a protein known for its role in cellular membrane dynamics and intracellular trafficking processes. This antibody, generated in rabbits, is highly specific for human SNX18 and has been validated for use in Western blot applications.SNX18 is a member of the sorting nexin family, which are involved in endosomal sorting and membrane trafficking. Research has shown that SNX18 plays a critical role in regulating membrane curvature and vesicle formation, making it a key player in cellular processes such as receptor recycling and protein trafficking. By targeting SNX18 with this antibody, researchers can study its localization and function in various cell types, shedding light on its role in cellular physiology and disease pathogenesis.
The Sorting Nexin 18 Polyclonal Antibody is a powerful tool for scientists investigating the molecular mechanisms underlying cellular trafficking, membrane dynamics, and organelle biogenesis. Its high specificity and reactivity make it an ideal choice for studies in cell biology, molecular biology, and related fields. Researchers working in areas such as cell signaling, membrane biology, and cancer research will find this antibody indispensable for their experiments and data analysis.
Product Name:
SNX18 Rabbit Polyclonal Antibody
SKU:
CAB10337
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 445-624 of human SNX18 (NP_001096045.1).
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
112574
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SNX18 antibody (CAB10337) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
