SORL1 Rabbit Polyclonal Antibody (CAB13047)
- SKU:
- CAB13047
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SORL1 Rabbit Polyclonal Antibody |
SKU: | CAB13047 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2065-2214 of human SORL1 (NP_003096.1). |
Sequence: | DSAM NITA YLGN TTDN FFKI SNLK MGHN YTFT VQAR CLFG NQIC GEPA ILLY DELG SGAD ASAT QAAR STDV AAVV VPIL FLIL LSLG VGFA ILYT KHRR LQSS FTAF ANSH YSSR LGSA IFSS GDDL GEDD EDAP MITG FSDD VPMV IA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | LR11; LRP9; SORLA; gp250; SorLA-1; C11orf32; SORL1 |
Positive Sample: | SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | Endosome, Golgi apparatus, Membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 248kDa |
Observed MW: | 260kDa |
This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease.
Purification Method: | Affinity purification |
Gene ID: | 6653 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |