SORD Rabbit Polyclonal Antibody (CAB2118)
- SKU:
- CAB2118
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SORD Rabbit Polyclonal Antibody |
SKU: | CAB2118 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 145-300 of human Sorbitol Dehydrogenase (NP_003095.2). |
Sequence: | DNVT FEEG ALIE PLSV GIHA CRRG GVTL GHKV LVCG AGPI GMVT LLVA KAMG AAQV VVTD LSAT RLSK AKEI GADL VLQI SKES PQEI ARKV EGQL GCKP EVTI ECTG AEAS IQAG IYAT RSGG NLVL VGLG SEMT TVPL LHAA IREV DIKG VFRY |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | RDH; SDH; XDH; SORD1; SORDD; HEL-S-95n; Sorbitol Dehydrogenase |
Positive Sample: | HeLa,HT-29,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Mitochondrion membrane, Peripheral membrane protein, cilium, flagellum. |
Calculated MW: | 38kDa |
Observed MW: | 38kDa |
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Purification Method: | Affinity purification |
Gene ID: | 6652 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |