Sorbitol Dehydrogenase Monoclonal Antibody (CAB21952)
- SKU:
- CAB21952
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | Sorbitol Dehydrogenase Monoclonal Antibody |
SKU: | CAB21952 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Sorbitol Dehydrogenase (NP_003095.2). |
Sequence: | REND EFCK MGRY NLSP SIFF CATP PDDG NLCR FYKH NAAF CYKL PDNV TFEE GALI EPLS VGIH ACRR GGVT LGHK VLVC GAGP IGMV TLLV AKAM GAAQ V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:20000 |
Synonyms: | RDH; SDH; XDH; SORD1; SORDD; HEL-S-95n; Sorbitol Dehydrogenase |
Positive Sample: | HT-29,Mouse kidney,Mouse liver,Rat kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Mitochondrion membrane, Peripheral membrane protein, cilium, flagellum. |
Calculated MW: | 38kDa |
Observed MW: | 38kDa |
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Purification Method: | Affinity purification |
Gene ID: | 6652 |
Clone Number: | ARC53945 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |