The SON Polyclonal Antibody (CAB16323) is a vital tool for researchers studying the SON protein, which plays a crucial role in RNA splicing and transcription regulation. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting SON protein in human samples, particularly in Western blot applications.By binding specifically to the SON protein, this antibody enables precise detection and analysis of SON expression in various cell types, making it an essential asset for investigations in molecular biology and cancer research.
The SON protein is known for its involvement in cellular processes such as DNA replication and repair, making it a key player in maintaining genomic stability.Research on the SON protein is essential for understanding its functional roles in gene regulation and disease pathogenesis, particularly in conditions like cancer and genetic disorders. By studying the SON protein, researchers can gain valuable insights into its potential as a therapeutic target for developing treatments that target aberrant gene expression and cellular dysregulation.
Product Name:
SON Rabbit Polyclonal Antibody
SKU:
CAB16323
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 850-950 of human SON (NP_001278340.1).
This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6651
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SON Rabbit pAb (CAB16323) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 8min.
