The Somatostatin Polyclonal Antibody (CAB9274) is a valuable tool for researchers studying somatostatin, a peptide hormone involved in the regulation of various physiological functions in the body. This antibody, raised in rabbits, is highly specific to somatostatin and has been validated for use in immunohistochemistry and Western blot applications.Somatostatin is known for its inhibitory effects on hormone secretion, cell proliferation, and neurotransmission. It plays a crucial role in the regulation of growth hormone, insulin, glucagon, and other hormones, making it a key player in endocrine function. The somatostatin antibody allows for the detection and analysis of somatostatin expression in different tissues and cell types, providing researchers with valuable insights into its role in health and disease.
Research on somatostatin has implications for various medical fields, including endocrinology, neuroscience, and gastroenterology. By understanding the mechanisms of somatostatin action, researchers may uncover potential therapeutic targets for conditions such as hormone imbalances, neuroendocrine tumors, and gastrointestinal disorders. The Somatostatin Polyclonal Antibody is an essential tool for advancing our understanding of somatostatin's diverse functions and its potential as a therapeutic target.
Product Name:
Somatostatin (SST) Rabbit Polyclonal Antibody
SKU:
CAB9274
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-116 of human SST (NP_001039.1).
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.
Purification Method:
Affinity purification
Gene ID:
6750
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat brain, using Somatostatin (SST) Rabbit pAb (CAB9274) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
