The SOHLH2 Polyclonal Antibody (PAC041450) is a valuable tool for researchers studying SOHLH2, a key transcription factor involved in germ cell development. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It specifically binds to the SOHLH2 protein, enabling accurate detection and analysis in a variety of cell types.SOHLH2 plays a crucial role in regulating germ cell development and differentiation, making it a significant target for research in reproductive biology and infertility.
Dysregulation of SOHLH2 has been linked to various reproductive disorders, making it a potential biomarker for diagnosing and treating infertility in both men and women. Understanding the function of SOHLH2 is essential for developing new strategies for fertility preservation and treatment.Overall, the SOHLH2 Polyclonal Antibody is a valuable research tool for scientists investigating the role of SOHLH2 in germ cell development and infertility, providing reliable and accurate detection for a wide range of research applications.
Antibody Name:
SOHLH2 Antibody (PACO41450)
Antibody SKU:
PACO41450
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 protein (1-225AA)
Immunohistochemistry of paraffin-embedded human breast cancer using PACO41450 at dilution of 1:100.
Background:
Probable transcription factor, which may be involved in spermatogenesis and oogenesis.
Synonyms:
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2, SOHLH2, TEB1
UniProt Protein Function:
SOHLH2: Probable transcription factor, which may be involved in spermatogenesis and oogenesis. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 13q13.3Cellular Component: nucleusBiological Process: cell differentiation; transcription from RNA polymerase II promoter
UniProt Protein Details:
NCBI Summary:
This locus represents naturally occurring read-through transcription between the neighboring C13orf38 (chromosome 13 open reading frame 38) and SOHLH2 (spermatogenesis and oogenesis specific basic helix-loop-helix 2) genes. The read-through transcript encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Nov 2010]
