SOD3 Rabbit Polyclonal Antibody (CAB6984)
- SKU:
- CAB6984
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | SOD3 Rabbit Polyclonal Antibody |
SKU: | CAB6984 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 19-160 of human SOD3 (NP_003093.2). |
Sequence: | WTGE DSAE PNSD SAEW IRDM YAKV TEIW QEVM QRRD DDGA LHAA CQVQ PSAT LDAA QPRV TGVV LFRQ LAPR AKLD AFFA LEGF PTEP NSSS RAIH VHQF GDLS QGCE STGP HYNP LAVP HPQH PGDF GNFA VRDG SLWR YR |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | EC-SOD; SOD3 |
Positive Sample: | 22Rv1,HL-60,Mouse kidney,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular space. |
Calculated MW: | 26kDa |
Observed MW: | 35kDa |
This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk.
Purification Method: | Affinity purification |
Gene ID: | 6649 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |