[KO Validated] SOD2 Rabbit Polyclonal Antibody (CAB1340)
- SKU:
- CAB1340
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] SOD2 Rabbit Polyclonal Antibody |
SKU: | CAB1340 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2). |
Sequence: | KHSL PDLP YDYG ALEP HINA QIMQ LHHS KHHA AYVN NLNV TEEK YQEA LAKG DVTA QIAL QPAL KFNG GGHI NHSI FWTN LSPN GGGE PKGE LLEA IKRD FGSF DKFK EKLT AASV GVQG SGWG WLGF NKER GHLQ IAAC PNQD PLQG TTGL IPLL GIDV WEHA YYLQ YKNV RPDY LKAI WNVI NWEN VTER YMAC KK |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | GC1; IPOB; IPO-B; MNSOD; MVCD6; GClnc1; Mn-SOD; D2 |
Positive Sample: | 293T,HepG2,A-549,Mouse liver,Mouse brain,Mouse heart,Rat liver,Rat brain,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 25kDa |
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
Purification Method: | Affinity purification |
Gene ID: | 6648 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |