SOD1 Monoclonal Antibody [PAT6F1AT] (CPAB0228)
- SKU:
- CPAB0228
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT6F1AT
- Applications:
- ELISA
- FC
Description
SOD1 Monoclonal Antibody [PAT6F1AT] (CPAB0228)
The SOD1 Polyclonal Antibody (CPAB0228) is a valuable tool for researchers studying superoxide dismutase 1 (SOD1), an important enzyme involved in antioxidant defense and cell protection. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the SOD1 protein, this antibody enables accurate detection and analysis in various cell types, providing researchers with valuable insights into oxidative stress, neurodegenerative diseases, and other conditions related to SOD1 activity.
SOD1 is a critical enzyme that plays a key role in neutralizing harmful superoxide radicals and protecting cells from oxidative damage. Dysregulation of SOD1 activity has been linked to a variety of diseases, including amyotrophic lateral sclerosis (ALS) and familial amyotrophic lateral sclerosis (FALS). By studying the expression and function of SOD1 using this antibody, researchers can gain a better understanding of the underlying mechanisms of these diseases and potentially identify new therapeutic targets for treatment.
Product Name: | SOD1 Antibody |
Product Sku: | CPAB0228 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human SOD1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SOD1 protein 1-154 amino acids purified from Ecoli. |
Clone: | PAT6F1AT. |
Reactivity: | Human |
Applications: | ELISA, Flow Cytometry |
Purification Method: | SOD1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | Human Cu/Zn Superoxide Dismutase (SOD1) catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide. SOD1 binds copper and zinc ions and is 1 of 3 isozymes accountable for destroying free superoxide radicals in the body. The encoded protein neutralizes supercharged oxygen molecules, which can damage cells if their levels are not controlled. Mutations in SOD1 cause a form of familial amyotrophic lateral sclerosis. |
Synonyms: | Superoxide dismutase [Cu-Zn], EC 1.15.1.1, SOD1, SOD, ALS, ALS1, IPOA. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |