SOCS6 Rabbit Polyclonal Antibody (CAB9957)
- SKU:
- CAB9957
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | SOCS6 Rabbit Polyclonal Antibody |
SKU: | CAB9957 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SOCS6 (NP_004223.2). |
Sequence: | MKKI SLKT LRKS FNLN KSKE ETDF MVVQ QPSL ASDF GKDD SLFG SCYG KDMA SCDI NGED EKGG KNRS KSES LMGT LKRR LSAK QKSK GKAG TPSG SSAD EDTF SSSS APIV FKDV RAQR PIRS TSLR SHHY SPAP WPLR PTNS EETC IKME VRVK ALVH SSSP SPAL NGVR KDFH DLQS ETTC QEQA NSLK SSAS HNGD LHLH LDEH VP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | CIS4; SSI4; CIS-4; SOCS4; STAI4; SOCS-4; SOCS-6; STATI4; HSPC060; SOCS6 |
Positive Sample: | A-549,Mouse heart,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, immunological synapse |
Calculated MW: | 60kDa |
Observed MW: | 70kDa |
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
Purification Method: | Affinity purification |
Gene ID: | 9306 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |