The SOCS5 Polyclonal Antibody (CAB7952) is a valuable tool for researchers studying the SOCS5 protein, a member of the Suppressor of Cytokine Signaling (SOCS) family known for its role in regulating the immune response and cell growth. Raised in rabbits, this antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications.SOCS5 is a key player in the negative regulation of cytokine signaling pathways, controlling the intensity and duration of immune responses. Dysregulation of SOCS5 has been linked to various diseases, including cancer and autoimmune disorders, making it a promising target for therapeutic interventions.
By detecting and analyzing SOCS5 protein expression in different cell types, this antibody facilitates in-depth research in the fields of immunology and oncology.The versatility and specificity of the SOCS5 Polyclonal Antibody make it an indispensable tool for investigators seeking to elucidate the complex mechanisms underlying immune regulation and cell signaling pathways. Its application in various experimental settings enables scientists to explore the potential implications of SOCS5 in disease pathogenesis and develop novel strategies for targeted therapy.
Product Name:
SOCS5 Rabbit Polyclonal Antibody
SKU:
CAB7952
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SOCS5 (NP_054730.1).
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.
Purification Method:
Affinity purification
Gene ID:
9655
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SOCS5 Rabbit pAb (CAB7952) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
