The SNX5 Polyclonal Antibody (CAB13160) is a powerful tool for researchers studying the sorting nexin 5 (SNX5) protein, a key player in endosomal trafficking and sorting processes. This antibody, raised in rabbits, exhibits high specificity and sensitivity in detecting SNX5 in human samples, making it an essential component for Western blot analysis.SNX5 is essential for the regulation of endosomal sorting and recycling pathways, impacting cellular processes such as receptor trafficking, protein degradation, and signaling cascades. By targeting SNX5 with this antibody, researchers can gain valuable insights into the mechanisms underlying these processes and their implications in various cellular functions and diseases.
With its ability to specifically bind to SNX5, this polyclonal antibody enables precise detection and analysis of SNX5 in a variety of cell types, paving the way for advancements in cell biology, membrane trafficking, and disease research. Its versatility and reliability make it a valuable asset for investigating the role of SNX5 in normal cellular function and disease pathology.
Product Name:
SNX5 Rabbit Polyclonal Antibody
SKU:
CAB13160
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 145-404 of human SNX5 (NP_055241.1).
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
27131
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SNX5 Rabbit pAb (CAB13160) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
