The SNX3 Polyclonal Antibody (CAB13380) is a valuable tool for researchers studying the SNX3 protein, a key player in endosomal sorting and membrane trafficking pathways. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it an ideal choice for various experimental applications.SNX3 is a crucial component in the retromer complex, which is involved in the retrieval of transmembrane proteins from endosomes to the trans-Golgi network. Dysregulation of SNX3 has been implicated in various diseases, including neurodegenerative disorders and cancer.
By targeting SNX3 with this antibody, researchers can gain insights into its role in cellular processes and disease pathogenesis.With its proven efficacy in Western blotting, immunohistochemistry, and other techniques, the SNX3 Polyclonal Antibody is a versatile tool for investigating the functions and mechanisms of SNX3 in both normal and diseased conditions. Researchers in the fields of cell biology, molecular biology, and neurology will find this antibody indispensable for their studies.
Product Name:
SNX3 Rabbit Polyclonal Antibody
SKU:
CAB13380
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-162 of human SNX3 (NP_003786.1).
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. A pseudogene of this gene is present on the sex chromosomes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
8724
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SNX3 antibody (CAB13380) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
