The SNX29 Polyclonal Antibody (PAC020572) is a valuable tool for research involving SNX29, a member of the sorting nexin (SNX) family of proteins known for their role in intracellular trafficking and membrane dynamics. This antibody, generated in rabbits, exhibits high specificity and sensitivity for SNX29 in human samples, making it suitable for use in Western blot applications.SNX29 is involved in endosomal sorting processes and has been implicated in various cellular functions, including receptor recycling and signaling pathways. By targeting SNX29, researchers can investigate its role in protein trafficking and cellular communication, providing insights into its potential involvement in diseases such as cancer, neurodegenerative disorders, and metabolic conditions.
Understanding the function of SNX29 is essential for unraveling its impact on cellular physiology and disease pathogenesis. With the SNX29 Polyclonal Antibody, researchers can explore the intricate mechanisms underlying SNX29-mediated processes, paving the way for innovative discoveries in cell biology and therapeutic interventions.
Antibody Name:
SNX29 Antibody (PACO20572)
Antibody SKU:
PACO20572
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:20-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human SNX29
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20572(SNX29 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
SNX29 also known as RUNDC2A, is a 375 amino protein that contains one RUN domain. RUNDC2A is encoded by a gene that maps to human chromosome 16p13.13, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Synonyms:
sorting nexin 29
UniProt Protein Function:
SNX29: Belongs to the sorting nexin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: VesicleChromosomal Location of Human Ortholog: 16p13.13-p13.12
