SNX27 Antibody (PACO12382)
- SKU:
- PACO12382
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
SNX27 Antibody (PACO12382)
The SNX27 Polyclonal Antibody (PACO12382) is a valuable tool for researchers studying SNX27, a crucial protein involved in endocytic trafficking and signaling pathways. This antibody, produced in rabbits, is highly specific and reacts strongly with human samples, making it suitable for various applications including Western blotting and immunofluorescence.SNX27 is a key player in the sorting and recycling of cell surface receptors, as well as in the regulation of signaling cascades that control cell growth and differentiation.
By targeting SNX27, researchers can delve deeper into understanding the mechanisms underlying cell trafficking and signaling, providing insights into diseases such as cancer, neurological disorders, and metabolic syndromes.With its high specificity and sensitivity, the SNX27 Polyclonal Antibody is a reliable tool for investigating the functions of SNX27 in cellular processes, making it a valuable asset for studies in cell biology and disease mechanisms.
| Antibody Name: | SNX27 Antibody (PACO12382) |
| Antibody SKU: | PACO12382 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human SNX27 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | sorting nexin family member 27;SNX27;KIAA0488;MGC126871;MGC126873;MGC20471;MRT1;MY014 ; |
| UniProt Protein Function: | SNX27: Involved in endocytic trafficking. In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes. Belongs to the sorting nexin family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: cytoplasm; early endosome; immunological synapse; nucleoplasm; retromer complex Molecular Function:phosphatidylinositol 3-phosphate binding; protein binding Biological Process: endosome transport; establishment of natural killer cell polarity; intracellular protein transport |
| NCBI Summary: | This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96L92 |
| NCBI GenInfo Identifier: | 166214988 |
| NCBI Gene ID: | 81609 |
| NCBI Accession: | Q96L92.2 |
| UniProt Secondary Accession: | Q96L92,Q32Q36, Q4AEJ5, Q5VWB0, Q5VWB1, Q5VWB2, Q6IPP6 Q86UB1, Q96D79, Q9H3K8, |
| UniProt Related Accession: | Q96L92 |
| Molecular Weight: | 27,781 Da |
| NCBI Full Name: | Sorting nexin-27 |
| NCBI Synonym Full Names: | sorting nexin family member 27 |
| NCBI Official Symbol: | SNX27Â Â |
| NCBI Official Synonym Symbols: | MRT1; MY014Â Â |
| NCBI Protein Information: | sorting nexin-27 |
| UniProt Protein Name: | Sorting nexin-27 |
| Protein Family: | Sorting nexin |
| UniProt Gene Name: | SNX27Â Â |
| UniProt Entry Name: | SNX27_HUMAN |
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