The SNX16 Polyclonal Antibody (PACO30044) is a valuable tool for researchers studying SNX16, a key protein involved in intracellular trafficking and membrane dynamics. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the SNX16 protein, this antibody allows for the detection and analysis of SNX16 expression in various cell types, making it an essential tool for studies in cell biology and molecular biology.SNX16 plays a crucial role in the sorting and recycling of membrane proteins, as well as in the regulation of endosomal trafficking pathways.
Its function in vesicle transport and membrane remodeling makes it a pivotal player in cell physiology and signaling pathways. Research on SNX16 is instrumental in understanding cell dynamics, organelle biogenesis, and protein trafficking mechanisms, with implications for diseases like neurodegenerative disorders, metabolic syndromes, and infectious diseases. The SNX16 Polyclonal Antibody is a reliable reagent for investigating the role of SNX16 in cellular processes and disease pathology.
Antibody Name:
SNX16 Antibody (PACO30044)
Antibody SKU:
PACO30044
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Sorting nexin-16 protein (1-342AA)
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO30044 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO30044 at dilution of 1:100.
Background:
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
Synonyms:
Sorting nexin-16, SNX16
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The function of this protein has not been determined. This gene results in three transcript variants encoding two distinct isoforms. [provided by RefSeq, Jul 2008]
