SNX15 Rabbit Polyclonal Antibody (CAB9158)
- SKU:
- CAB9158
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | SNX15 Rabbit Polyclonal Antibody |
SKU: | CAB9158 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human SNX15 (NP_037438.2). |
Sequence: | MSRQ AKDD FLRH YTVS DPRT HPKG YTEY KVTA QFIS KKDP EDVK EVVV WKRY SDFR KLHG DLAY THRN LFRR LEEF PAFP RAQV FGRF EASV IEER RKGA EDLL RFTV HIPA LNNS PQLK EFFR GGEV TRPL EVSR DLHI LPPP LIPT PPPD DPRL SQLL PAER RGLE ELEV PVDP PPSS PAQE ALDL LFNC ESTE EASG SPAR GPLT EAEL ALFD PFSK EEGA APSP THVA ELAT MEVE SARL DQEP WEPG GQEE EEDG EGGP TPAY LSQA TELI TQAL RDEK AGAY AAAL QGYR DGVH VLLQ GVPS DPLP ARQE GVKK KAAE YLKR AEEI LRLH LSQL PP |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | HSAF001435; SNX15 |
Positive Sample: | U-87MG,HepG2,Jurkat,Raji,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle membrane, Membrane, Peripheral membrane protein. |
Calculated MW: | 38kDa |
Observed MW: | 50kDa |
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.
Purification Method: | Affinity purification |
Gene ID: | 29907 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |