SNX13 Rabbit Polyclonal Antibody (CAB12821)
- SKU:
- CAB12821
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | SNX13 Rabbit Polyclonal Antibody |
SKU: | CAB12821 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human SNX13 (NP_055947.1). |
Sequence: | FGKT NSEK YLEQ CEHS FLPP TSPG VPKC LEEM KREA RTIK IDRR LTGA NIID EPLQ QVIQ FSLR DYVQ YWYY TLSD DESF LLEI RQTL QNAL IQFA TRSK EIDW QPYF TTRI VDDF GTHL RVFR KAQQ KITE KDDQ VKGT AEDL VDTF FEVE VEME KEVC RDLV CTSP KDEE GFLR DLCE V |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | RGS-PX1; SNX13 |
Positive Sample: | U-87MG,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic side, Early endosome membrane, Peripheral membrane protein. |
Calculated MW: | 112kDa |
Observed MW: | 112kDa |
This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.
Purification Method: | Affinity purification |
Gene ID: | 23161 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |