The SNW1 Polyclonal Antibody (CAB14580) is a valuable tool for researchers studying the SNW1 protein, which plays a key role in RNA splicing and gene regulation. This antibody, developed using rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.SNW1 is a multifunctional protein involved in various cellular processes, including transcriptional regulation and mRNA processing. Its role in splicing and gene expression makes it an important target for research in molecular biology and biotechnology. By binding to the SNW1 protein, this antibody enables the detection and analysis of SNW1 expression in a variety of cell types.
Researchers studying RNA processing, gene regulation, and related pathways will benefit from the use of the SNW1 Polyclonal Antibody in their experiments. Understanding the function of SNW1 can provide insights into disease processes and potential therapeutic targets in conditions such as cancer and genetic disorders. This antibody is a valuable tool for advancing research in these areas and uncovering new opportunities for medical interventions.
Product Name:
SNW1 Rabbit Polyclonal Antibody
SKU:
CAB14580
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-536 of human SNW1 (NP_036377.1).
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
22938
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SNW1 Rabbit pAb (CAB14580) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
