SNW1 Rabbit Polyclonal Antibody (CAB14580)
- SKU:
- CAB14580
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | SNW1 Rabbit Polyclonal Antibody |
SKU: | CAB14580 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-536 of human SNW1 (NP_036377.1). |
Sequence: | EAVE MRAQ VERK MAQK EKEK HEEK LREM AQKA RERR AGIK THVE KEDG EARE RDEI RHDR RKER QHDR NLSR AAPD KRSK LQRN ENRD ISEV IALG VPNP RTSN EVQY DQRL FNQS KGMD SGFA GGED EIYN VYDQ AWRG GKDM AQSI YRPS KNLD KDMY GDDL EARI KTNR FVPD KEFS GSDR RQRG REGP VQFE EDPF GLDK FLEE AKQH GGSK RPSD SSRP KEHE HEGK KRRK E |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:200 |
Synonyms: | Bx42; SKIP; FUN20; Prp45; SKIIP; SKIP1; PRPF45; NCOA-62; SNW1 |
Positive Sample: | 22Rv1,293T,HeLa,HepG2,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 61kDa |
Observed MW: | 70kDa/75kDa |
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 22938 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |