Anti-SNRPD1 Antibody (CAB7216)
- SKU:
- CAB7216
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Anti-SNRPD1 Antibody (CAB7216)
The SNRPD1 Polyclonal Antibody (CAB7216) is a valuable tool for research related to SNRPD1, a core component of the spliceosome complex involved in RNA splicing. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By targeting the SNRPD1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and genetics.SNRPD1 is essential for the splicing of pre-mRNA molecules into mature mRNA, playing a key role in gene expression regulation. Dysregulation of this process can lead to various diseases, including cancer and genetic disorders.
Investigating the function of SNRPD1 can provide critical insights into the mechanisms underlying these conditions and may lead to the development of novel therapeutic strategies targeting RNA splicing pathways.Overall, the SNRPD1 Polyclonal Antibody is a valuable resource for researchers interested in studying RNA splicing and its implications in disease pathology. Its specificity and reliability make it a valuable asset for advancing our understanding of gene expression and its role in human health and disease.
| Antibody Name: | Anti-SNRPD1 Antibody |
| Antibody SKU: | CAB7216 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human SNRPD1 (NP_008869.1). |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:100 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human SNRPD1 (NP_008869.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MKLV RFLM KLSH ETVT IELK NGTQ VHGT ITGV DVSM NTHL KAVK MTLK NREP VQLE TLSI RGNN IRYF ILPD SLPL DTLL VDVE PKVK SKKR EAVA GRGR GRGR GRGR GRGR GRGG PRR |
| Gene ID: | 6632 |
| Uniprot: | P62314 |
| Cellular Location: | Cytoplasm, Nucleus, cytosol |
| Calculated MW: | 13kDa |
| Observed MW: |
| Synonyms: | SNRPD1, HsT2456, SMD1, SNRPD, Sm-D1 |
| Background: | This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | snRNP D1: May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA. Belongs to the snRNP core protein family. |
| UniProt Protein Details: | Protein type:RNA splicing; Spliceosome; RNA-binding Chromosomal Location of Human Ortholog: 18q11.2 Cellular Component: nucleoplasm; small nuclear ribonucleoprotein complex; snRNP U1; cytosol; nucleus; U12-dependent spliceosome Molecular Function:protein binding; RNA binding Biological Process: nuclear mRNA splicing, via spliceosome; spliceosomal snRNP biogenesis; RNA splicing; spliceosome assembly; gene expression |
| NCBI Summary: | This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] |
| UniProt Code: | P62314 |
| NCBI GenInfo Identifier: | 51338665 |
| NCBI Gene ID: | 6632 |
| NCBI Accession: | P62314.1 |
| UniProt Secondary Accession: | P62314,P13641, B5BTZ1, |
| UniProt Related Accession: | P62314 |
| Molecular Weight: | 119 |
| NCBI Full Name: | Small nuclear ribonucleoprotein Sm D1 |
| NCBI Synonym Full Names: | small nuclear ribonucleoprotein D1 polypeptide 16kDa |
| NCBI Official Symbol: | SNRPD1Â Â |
| NCBI Official Synonym Symbols: | SMD1; SNRPD; Sm-D1; HsT2456Â Â |
| NCBI Protein Information: | small nuclear ribonucleoprotein Sm D1; Sm-D autoantigen; snRNP core protein D1; small nuclear ribonucleoprotein D1 polypeptide 16kDa pseudogene |
| UniProt Protein Name: | Small nuclear ribonucleoprotein Sm D1 |
| UniProt Synonym Protein Names: | Sm-D autoantigen; snRNP core protein D1 |
| Protein Family: | Small nuclear ribonucleoprotein |
| UniProt Gene Name: | SNRPD1Â Â |
| UniProt Entry Name: | SMD1_HUMAN |
 | Immunofluorescence analysis of MCF-7 cells using SNRPD1 antibody (CAB7216). |
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