The SNRPB2 Polyclonal Antibody (CAB8908) is a valuable tool for researchers studying SNRPB2, a key protein involved in pre-mRNA splicing. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting SNRPB2 in human samples, making it ideal for use in Western blot applications.SNRPB2 is a core component of the spliceosome, a complex molecular machine responsible for removing introns from pre-mRNA to generate mature mRNA. Dysregulation of SNRPB2 has been linked to various diseases, including cancer and neurological disorders, highlighting its importance in cellular processes.
By utilizing the SNRPB2 Polyclonal Antibody, researchers can gain insights into the function and regulation of SNRPB2 in different cell types and disease contexts. This antibody enables precise detection and analysis of SNRPB2, facilitating further investigations into the role of this protein in RNA splicing and disease development.
Product Name:
SNRPB2 Rabbit Polyclonal Antibody
SKU:
CAB8908
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human SNRPB2 (NP_003083.1).
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6629
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SNRPB2 antibody (CAB8908) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
