U1A/SNRPA Rabbit Polyclonal Antibody (CAB6410)
- SKU:
- CAB6410
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | U1A/SNRPA Rabbit Polyclonal Antibody |
SKU: | CAB6410 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human U1A/U1A/SNRPA (NP_004587.1). |
Sequence: | MAVP ETRP NHTI YINN LNEK IKKD ELKK SLYA IFSQ FGQI LDIL VSRS LKMR GQAF VIFK EVSS ATNA LRSM QGFP FYDK PMRI QYAK TDSD IIAK MKGT FVER DRKR EKRK PKSQ ETPA TKKA VQGG GATP VVGA VQGP VPGM PPMT QAPR IMHH MPGQ PPYM PPPG MIPP PGLA PGQI PPGA MPPQ QLMP GQMP PAQP LSEN PPNH ILFL TNLP EETN ELML SMLF NQFP GFKE VRLV PGRH DIAF VEFD NEVQ AGAA RDAL QGFK ITQN NAMK ISFA KK |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | U1A; Mud1; U1-A; U1A/SNRPA |
Positive Sample: | Jurkat,293T,A-431,MCF7,Mouse brain,Mouse testis,Mouse thymus,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 31kDa |
Observed MW: | 31kDa |
The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
Purification Method: | Affinity purification |
Gene ID: | 6626 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |