The SNRNP70 Polyclonal Antibody (CAB6065) is a vital tool for research focused on SNRNP70, a key component of the spliceosome complex involved in pre-mRNA splicing. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it ideal for use in Western blot applications. By binding to the SNRNP70 protein, this antibody enables accurate detection and analysis in a variety of cell types, offering valuable insights for studies in molecular biology and RNA processing.
SNRNP70 is integral to the splicing process, playing a crucial role in the removal of introns from pre-mRNA molecules to generate mature mRNA transcripts. Dysregulation of this splicing factor has been linked to various diseases, including cancer and genetic disorders, making it a promising target for therapeutic intervention. By understanding the functions of SNRNP70, researchers can uncover new strategies for treating conditions related to aberrant RNA splicing mechanisms.
Product Name:
SNRNP70 Rabbit Polyclonal Antibody
SKU:
CAB6065
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SNRNP70 (NP_003080.2).
Enables U1 snRNA binding activity. Involved in mRNA splicing, via spliceosome and regulation of RNA splicing. Located in nucleoplasm. Part of U1 snRNP and spliceosomal complex. Implicated in disease of mental health and systemic lupus erythematosus. Biomarker of Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
6625
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SNRNP70 Rabbit pAb (CAB6065) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
