The SNRNP35 Polyclonal Antibody (CAB13211) is a valuable tool for researchers studying SNRNP35, a crucial component of the spliceosome complex involved in mRNA splicing. This antibody, produced through the immunization of rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By targeting the SNRNP35 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and gene expression.SNRNP35 plays a key role in the splicing of pre-mRNA, making it essential for proper gene expression and cell function.
Dysregulation of this process has been linked to various diseases, including cancer and genetic disorders. By investigating the function and regulation of SNRNP35, researchers can gain valuable insights into the underlying mechanisms of these conditions and potentially develop targeted therapies.Overall, the SNRNP35 Polyclonal Antibody (CAB13211) offers researchers a reliable tool for studying the intricate processes of mRNA splicing and gene expression, paving the way for advancements in biomedical research and potential therapeutic interventions.
Product Name:
SNRNP35 Rabbit Polyclonal Antibody
SKU:
CAB13211
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human SNRNP35 (NP_073208.1).
The protein encoded by this gene is a homolog of the U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal half is rich in Arg/Asp and Arg/Glu dipeptides, which is a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. Alternative splicing results in multiple transcript variants encoding two distinct isoforms and representing a non-protein coding variant.
Purification Method:
Affinity purification
Gene ID:
11066
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SNRNP35 Rabbit pAb (CAB13211) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
