SNRNP200 Rabbit Polyclonal Antibody (CAB6063)
- SKU:
- CAB6063
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | SNRNP200 Rabbit Polyclonal Antibody |
SKU: | CAB6063 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2). |
Sequence: | QMVT QAMW SKDS YLKQ LPHF TSEH IKRC TDKG VESV FDIM EMED EERN ALLQ LTDS QIAD VARF CNRY PNIE LSYE VVDK DSIR SGGP VVVL VQLE REEE VTGP VIAP LFPQ KREE GWWV VIGD AKSN SLIS IKRL TLQQ KAKV KLDF VAPA TGAH NYTL YFMS DAYM GCDQ EYKF SVDV KEAE TDSD SD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BRR2; RP33; HELIC2; ASCC3L1; U5-200KD; SNRNP200 |
Positive Sample: | Jurkat,A-431,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 245kDa |
Observed MW: | 244kDa |
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 23020 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |