The Syntaphilin Polyclonal Antibody (CAB12300) is a valuable tool for researchers studying the protein Syntaphilin, a key player in neuronal communication and synaptic plasticity. This antibody, produced in rabbits, shows high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to Syntaphilin, this antibody enables the detection and analysis of the protein in various cell types, making it an essential component for studies in neurobiology and synaptic function.Syntaphilin is a critical regulator of synaptic transmission and plasticity, making it an intriguing target for research into neurological disorders and cognitive function. Its function in anchoring mitochondria at synaptic sites and regulating their movement is essential for proper neuronal functioning.
Understanding the role of Syntaphilin in these processes is crucial for developing treatments for conditions such as Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.Overall, the Syntaphilin Polyclonal Antibody (CAB12300) is a reliable tool for researchers seeking to explore the intricate mechanisms of neuronal communication and synaptic plasticity. Its high reactivity and specificity make it an invaluable asset for studies aimed at unraveling the mysteries of the brain and developing novel therapeutic strategies for neurological conditions.
Product Name:
SNPH Rabbit Polyclonal Antibody
SKU:
CAB12300
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-425 of human SNPH (NP_055538.2).
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
9751
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse small intestine, using SNPH Rabbit pAb (CAB12300) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
