SNIP1 Rabbit Polyclonal Antibody (CAB16747)
- SKU:
- CAB16747
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SNIP1 Rabbit Polyclonal Antibody |
SKU: | CAB16747 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SNIP1 (NP_078976.2). |
Sequence: | SESQ ELVP RPGG NNKE KEVP AKEK PSFE LSGA LLED TNTF RGVV IKYS EPPE ARIP KKRW RLYP FKND EVLP VMYI HRQS AYLL GRHR RIAD IPID HPSC S |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PML1; PMRED; NEDHCS; SNIP1 |
Positive Sample: | BxPC-3 |
Cellular Localization: | cytosol, nucleoplasm, nucleus |
Calculated MW: | 46kDa |
Observed MW: | 46kDa |
This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).
Purification Method: | Affinity purification |
Gene ID: | 79753 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |