The SNIP1 Polyclonal Antibody (CAB16747) is a valuable tool for research involving the SNIP1 protein, a key player in gene transcription and regulation processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to SNIP1, researchers can effectively detect and analyze this protein in various cell types, making it suitable for studies in molecular biology and gene expression studies.SNIP1, also known as Smad nuclear interacting protein 1, is involved in regulating the activity of transcription factors and plays a critical role in cellular processes such as cell proliferation and differentiation.
Understanding the function of SNIP1 is essential for unraveling its significance in gene regulation and its potential implications in diseases such as cancer and developmental disorders. By targeting SNIP1 with this antibody, researchers can further explore its role in gene expression pathways and potentially uncover new therapeutic targets for various conditions.
Product Name:
SNIP1 Rabbit Polyclonal Antibody
SKU:
CAB16747
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SNIP1 (NP_078976.2).
This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).
Purification Method:
Affinity purification
Gene ID:
79753
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from BxPC-3 cells, using SNIP1 Rabbit pAb (CAB16747) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
