The SNF2H Rabbit Monoclonal Antibody (CAB3539) is a powerful tool for research involving SNF2H, a protein that plays a crucial role in chromatin remodeling and gene regulation. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity towards SNF2H in human samples, making it suitable for various applications, including Western blotting and immunofluorescence.SNF2H is a member of the SWI/SNF family of chromatin remodelers and is involved in DNA repair, transcriptional regulation, and genomic stability. Dysregulation of SNF2H has been linked to various diseases, including cancer and developmental disorders. By targeting SNF2H with this antibody, researchers can investigate its function in different cellular processes and gain insights into its potential as a therapeutic target.
This monoclonal antibody offers researchers a reliable tool for studying SNF2H in both basic and translational research settings. Its high affinity and specificity make it a valuable asset for uncovering the molecular mechanisms underlying SNF2H-mediated chromatin remodeling and its impact on gene expression regulation. By using this antibody, scientists can advance our understanding of SNF2H biology and potentially identify novel strategies for treating SNF2H-associated diseases.
Product Name:
SMARCA5/SNF2H Rabbit Monoclonal Antibody
SKU:
CAB3539
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 953-1052 of human SMARCA5/SNF2H (O60264).
Sequence:
RFLI CMLH KLGF DKEN VYDE LRQC IRNS PQFR FDWF LKSR TAME LQRR CNTL ITLI EREN MELE EKEK AEKK KRGP KPST QKRK MDGA PDGR GRKK KLKL
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein.
Purification Method:
Affinity purification
Gene ID:
8467
Clone Number:
ARC0795
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using SMARCA5/SMARCA5/SNF2H Rabbit mAb (CAB3539) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
