The SncG Polyclonal Antibody (CAB14492) is a valuable tool for researchers studying SncG, a protein associated with synaptic vesicle trafficking and neurotransmitter release. This antibody, developed using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SncG protein, this antibody allows for reliable detection and analysis in a variety of cell types, making it ideal for research in neuroscience and neurodegenerative diseases.SncG, also known as synuclein gamma, plays a crucial role in regulating synaptic vesicle exocytosis and neurotransmitter release, making it a key player in neuronal communication and function.
Dysregulation of SncG has been implicated in neurodegenerative disorders such as Parkinson's disease, making it a promising target for therapeutic development. By studying the functions of SncG, researchers can gain valuable insights into the mechanisms underlying neurodegeneration and potentially identify new treatment strategies for these debilitating conditions.
Product Name:
gamma-Synuclein Rabbit Polyclonal Antibody
SKU:
CAB14492
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-127 of human gamma-Synuclein (NP_003078.2).
Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, perinuclear region, spindle.
Calculated MW:
13kDa
Observed MW:
16kDa
This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development.
Purification Method:
Affinity purification
Gene ID:
6623
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using gamma-Synuclein Rabbit pAb (CAB14492) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
