The SNAP91 Polyclonal Antibody (CAB6746) is a valuable tool for researchers studying SNAP91, a key protein involved in endocytosis and intracellular trafficking processes. This antibody, generated in a rabbit host, exhibits high specificity and sensitivity when used in Western blot applications on human samples. By binding to SNAP91, the antibody enables the detection and analysis of this protein in various cell types, making it an ideal choice for studies in cell biology and neuroscience.SNAP91, also known as clathrin assembly lymphoid myeloid leukemia protein (CALM), plays a crucial role in the formation of clathrin-coated vesicles and the internalization of membrane proteins.
Dysregulation of SNAP91 has been implicated in various diseases, including neurodegenerative disorders and cancer. As such, understanding the function and regulation of SNAP91 is essential for developing novel therapeutic strategies targeting these conditions.Overall, the SNAP91 Polyclonal Antibody (CAB6746) is a valuable tool for researchers looking to investigate the role of SNAP91 in cellular processes and disease pathology. Its high specificity and reactivity make it a reliable choice for studies aiming to unravel the complex mechanisms underlying endocytosis and intracellular trafficking.
Product Name:
SNAP91 Rabbit Polyclonal Antibody
SKU:
CAB6746
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human SNAP91 (NP_001229723.1).
Predicted to enable several functions, including SNARE binding activity; clathrin binding activity; and phosphatidylinositol binding activity. Acts upstream of or within regulation of clathrin-dependent endocytosis. Predicted to be located in several cellular components, including postsynaptic density; presynaptic endosome; and presynaptic membrane. Predicted to be extrinsic component of endosome membrane. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; cytoplasmic vesicle; and parallel fiber to Purkinje cell synapse. Predicted to be extrinsic component of presynaptic endocytic zone membrane. Biomarker of Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
9892
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SNAP91 antibody (CAB6746) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
